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Maintenance in progress
Biological Pathway
Cite
curcumin
TNF-α binding to TNFR1↑
TRADD/RIPK1 complex I assembly↑
cIAP1/2 depletion↓
RIPK1/RIPK3 necrosome formation↑
MLKL phosphorylation↑
plasma membrane rupture↑
immunogenic cell death↑
colorectal cancer
Score: 0.90
8 hops
Pathway Hops
INHIBITS
Confidence: 95%
INDUCES
Confidence: 95%
INHIBITS
Confidence: 95%
INHIBITS
Confidence: 95%
INHIBITS
Confidence: 95%
PHOSPHORYLATES
Confidence: 95%
INHIBITS
Confidence: 95%
INHIBITS
Confidence: 95%
Discovered by InTree.AI — analyzing 250M+ scientific papers
curcumin → colorectal cancer — Biological Pathway | InTree.AI | InTree