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Biological Pathway
Cite
curcumin
p300/CBP histone acetyltransferase activity inhibited by curcumin direct binding
p65(Lys310) acetylation by p300 reduced
NF-κB transcriptional coactivator complex disassembled
BCL-2 and survivin transcription reduced
survivin protein levels reduced
chromosomal passenger complex activity impaired
spindle assembly checkpoint override reduced
mitotic catastrophe elevated
colorectal cancer
Score: 0.90
9 hops
Pathway Hops
INHIBITS
Confidence: 95%
INHIBITS
Confidence: 95%
PHOSPHORYLATES
Confidence: 95%
PHOSPHORYLATES
Confidence: 95%
CAUSES
Confidence: 95%
ASSOCIATED WITH
Confidence: 95%
INHIBITS
Confidence: 95%
INDUCES
Confidence: 95%
INHIBITS
Confidence: 95%
Discovered by InTree.AI — analyzing 250M+ scientific papers
curcumin → colorectal cancer — Biological Pathway | InTree.AI | InTree