aspirin → inflammation — Biological Pathway | InTree.AI

Biological Pathway

aspirinAMPK(Thr172) activated by salicylateTSC2(Thr1387) phosphorylated by AMPKRheb-GTP loading reducedmTORC1 kinase activity suppressedS6K1(Thr389) phosphorylation reduced4E-BP1(Thr37/Thr46) phosphorylation reducedcap-dependent translation of HIF-1α and c-Myc reducedVEGF and cyclin D1 production reducedproliferative-inflammatory signaling attenuatedinflammation

Score: 0.8010 hops

Pathway Hops

INHIBITSConfidence: 95%

PHOSPHORYLATESConfidence: 95%

CAUSESConfidence: 95%

PHOSPHORYLATESConfidence: 95%

INHIBITSConfidence: 95%

Discovered by InTree.AI — analyzing 250M+ scientific papers