Metformin → Cancer — Biological Pathway | InTree.AI

Biological Pathway

MetforminPTEN phosphatase activity ↑PIP3 levels ↓AKT activity ↓FOXO1/3a nuclear retention ↑BIM/PUMA transcription ↑caspase-3 activation ↑apoptosis ↑Cancer

Score: 0.908 hops

Pathway Hops

INHIBITSConfidence: 95%

CAUSESConfidence: 95%

PHOSPHORYLATESConfidence: 95%

INHIBITSConfidence: 95%

ACTIVATESConfidence: 95%

SUPPRESSESConfidence: 95%

INHIBITSConfidence: 95%

Discovered by InTree.AI — analyzing 250M+ scientific papers

Under Maintenance

Under maintenance — back shortly

Maintenance in progress

Metformin → Cancer — Biological Pathway | InTree.AI | InTree