aspirin → inflammation — Biological Pathway | InTree.AI

Biological Pathway

aspirinAMPK(Thr172) phosphorylation elevated by salicylateACC(Ser79) phosphorylation by AMPK elevatedmalonyl-CoA levels reducedfatty acid oxidation increasedmitochondrial membrane potential stabilizedROS generation reducedNF-κB(p65) nuclear translocation reducedIL-8/MCP-1 secretion suppressedinflammation

Score: 0.909 hops

Pathway Hops

INHIBITSConfidence: 95%

PHOSPHORYLATESConfidence: 95%

CAUSESConfidence: 95%

INHIBITSConfidence: 95%

SUPPRESSESConfidence: 95%

INHIBITSConfidence: 95%

Discovered by InTree.AI — analyzing 250M+ scientific papers