Metformin → Cancer — Biological Pathway | InTree.AI

Biological Pathway

MetforminLKB1 kinase activity ↑AMPK activation ↑RAF1 phosphorylation ↓MEK1/2 activity ↓ERK1/2 activity ↓cyclin D1 expression ↓G1 cell cycle arrest ↑Cancer

Score: 0.808 hops

Pathway Hops

INHIBITSConfidence: 95%

PHOSPHORYLATESConfidence: 95%

INHIBITSConfidence: 95%

SUPPRESSESConfidence: 95%

INHIBITSConfidence: 95%

Discovered by InTree.AI — analyzing 250M+ scientific papers

Under Maintenance

Under maintenance — back shortly

Maintenance in progress

Metformin → Cancer — Biological Pathway | InTree.AI | InTree