aspirin → inflammation — Biological Pathway | InTree.AI

Biological Pathway

aspirinCOX-1(Ser530) irreversibly acetylatedarachidonic acid conversion to PGG2 blockedTXA2 biosynthesis reducedplatelet IP3 signaling diminishedNF-κB(p65/p50) nuclear translocation reducedIL-1β and TNF-α transcription suppressedneutrophil and monocyte recruitment attenuatedinflammation

Score: 0.908 hops

Pathway Hops

ACETYLATESConfidence: 95%

INHIBITSConfidence: 95%

PHOSPHORYLATESConfidence: 95%

INHIBITSConfidence: 95%

SUPPRESSESConfidence: 95%

Discovered by InTree.AI — analyzing 250M+ scientific papers