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Biological Pathway
Cite
Metformin
ERK1/2 activation ↑
AP-1 transcription factor activation ↑
MMP-2 secretion ↑
MMP-9 secretion ↑
extracellular matrix degradation ↑
basement membrane breach ↑
tumor invasion and metastasis ↑
Cancer
Score: 0.90
8 hops
Pathway Hops
INHIBITS
Confidence: 95%
INHIBITS
Confidence: 95%
INHIBITS
Confidence: 95%
SUPPRESSES
Confidence: 95%
INHIBITS
Confidence: 95%
PROMOTES
Confidence: 95%
ASSOCIATED WITH
Confidence: 95%
INHIBITS
Confidence: 95%
Discovered by InTree.AI — analyzing 250M+ scientific papers
Metformin → Cancer — Biological Pathway | InTree.AI | InTree