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Biological Pathway
Cite
Metformin
EGFR activation ↑
PI3K p110 recruitment ↑
PIP3 generation ↑
AKT(Thr308/Ser473) phosphorylation ↑
TSC1/2 inhibition ↑
mTORC1 activation ↑
cap-dependent translation ↑
Cancer
Score: 0.90
8 hops
Pathway Hops
INHIBITS
Confidence: 95%
ACTIVATES
Confidence: 95%
PHOSPHORYLATES
Confidence: 95%
PHOSPHORYLATES
Confidence: 95%
PHOSPHORYLATES
Confidence: 95%
INHIBITS
Confidence: 95%
ACTIVATES
Confidence: 95%
SUPPRESSES
Confidence: 95%
Discovered by InTree.AI — analyzing 250M+ scientific papers
Metformin → Cancer — Biological Pathway | InTree.AI | InTree