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Biological Pathway
Cite
EGFR
JAK1 activation ↑
STAT5 phosphorylation ↑
STAT5 nuclear translocation ↑
BCL-2 transcription ↑
cytochrome c release ↓
caspase-9 activation ↓
effector caspase cascade ↓
apoptosis
Score: 0.90
8 hops
Pathway Hops
SUPPRESSES
Confidence: 95%
PHOSPHORYLATES
Confidence: 95%
PHOSPHORYLATES
Confidence: 95%
PHOSPHORYLATES
Confidence: 95%
INHIBITS
Confidence: 95%
INHIBITS
Confidence: 95%
INHIBITS
Confidence: 95%
INHIBITS
Confidence: 95%
Discovered by InTree.AI — analyzing 250M+ scientific papers
EGFR → apoptosis — Biological Pathway | InTree.AI | InTree